What type of food is high in Tetrodotoxin?

Pufferfish, commonly known as fugu in Japan, are notorious for containing high levels of tetrodotoxin, a potent neurotoxin. This toxin is primarily found in the internal organs, skin, and sometimes in the muscles of the fish. Tetrodotoxin interferes with nerve function by blocking sodium channels, which can lead to severe poisoning, paralysis, and even death if ingested in sufficient quantities.

Pufferfish are unique in their ability to produce this toxin due to the specific bacteria in their environment or their diet, which may include certain algae. While some other types of seafood may carry toxins, the consumption of pufferfish poses a high risk due to the concentration of tetrodotoxin, making it one of the most dangerous and controversial foods worldwide. This distinction makes pufferfish the correct answer regarding foods high in tetrodotoxin.